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Sitagliptin (INN; previously identified as MK-0431 and marketed as sitagliptin phosphate under the trade name Januvia) is an oral antihyperglycemic (antidiabetic drug.A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic.Metformin Insulin Pioglitazone Incretins Sulfonylureas Gliptins Select Issues for side by side comparison Blood Sugar Daily Routine Daily Sugar Testing.Metformin is an orally administered biguanide derivative used to lower blood glucose concentrations in patients. Cro news Bioreagent news Press and Events. Email.